Millisecond Spike Timing Codes for Motor Control
نویسندگان
چکیده
منابع مشابه
For Motor Outputs, as for Sensory Inputs, Spike Timing Carries More Information than Spike Rate
One of the fundamental problems in neuroscience is understanding the relationship between neural activity and the behavior it produces. In the study of neurons that control motor systems, that output has typically been quantified in terms of firing rate, measured as the number of spikes per unit time. By contrast, for sensory systems, the firing pattern—how those spikes are temporally distribut...
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The spike-timing-dependent plasticity (STDP), a synaptic learning rule for encoding learning and memory, relies on relative timing of neuronal activity on either side of the synapse. GABAergic signaling has been shown to control neuronal excitability and consequently the spike timing, but whether GABAergic circuits rule the STDP remained unknown. Here we show that GABAergic signaling governs th...
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GABAergic inhibition via local interneurons may play a role in enhancing spike timing precision in principal cells, since it tends to eliminate the influence of initial conditions. However, both the number and the timing of inhibitory synaptic events may be variable across repeated trials. How does this variability affect the spike timing precision in principal neurons ? In this paper, we deriv...
متن کاملInhibitory control of spike timing precision 1
GABAergic inhibition via local interneurons may play a role in enhancing spike timing precision in principal cells, since it tends to eliminate the influence of initial conditions. However, both the number and the timing of inhibitory synaptic events may be variable across repeated trials. How does this variability affect the spike timing precision in principal neurons ? In this paper, we deriv...
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Long-term modification of synaptic strength is one of the basic mechanisms of memory formation and activity-dependent refinement of neural circuits. This idea was purposed by Hebb to provide a basis for the formation of a cell assembly. Repetitive correlated activity of pre-synaptic and post-synaptic neurons can induce long-lasting synaptic strength modification, the direction and extent of whi...
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ژورنال
عنوان ژورنال: Trends in Neurosciences
سال: 2018
ISSN: 0166-2236
DOI: 10.1016/j.tins.2018.08.010